Extending Myringotomy Patency with Topical Everolimus in Rats
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چکیده
منابع مشابه
Comparison of the Duration of Patency and Closure Rate between Laser-Assisted Myringotomy and Incisional Myringotomy in Infants with Acute Otitis Media
OBJECTIVES: There has been a renewed interest in myringotomy in recent years due to the limited results of antibiotic treatment and undesirable e ffects of ventilating tubes. The purpose of this study was to compare the duration of patency and closure rate between laser-assisted myringotomy (LAM) and incisional myringotomy (IM) applications in infants with acute otitis media (AOM). PATIENTS AND...
متن کاملRadiofrequency myringotomy with the topical use of mitomycin C: an experimental study.
OBJECTIVE To assess the use of radiofrequency myringotomy in combination with mitomycin C as an alternative myringotomy technique on rabbits. STUDY DESIGN Experimental animal research protocol. SETTING University of Crete, School of Medicine, Medical Experimental Education and Research Center. METHODS Radiofrequency myringotomies were performed under general anesthesia on both ears of 20 ...
متن کاملLate effects of topical anesthetics on the healing of guinea pig tympanic membranes after myringotomy.
BACKGROUND The optimal local anesthetic for myringotomies or the insertion of tympanostomy tubes in adults should be easy and rapid to use, be painless during application, provide good anesthesia, be reversible, be inexpensive, and not cause any long-term damage to the tympanic membrane (TM). OBJECTIVE To evaluate the histologic effects of topical anesthetic agents on the healing of the TM af...
متن کاملLaser Assisted Myringotomy and Tympanostomy
Insertion of a PET is indicated for continuous middle ear aeration in patients with chronic otitis media with effusion (OME). It is estimated that some 27 million cases of otitis media occur each year and that 1,000,000 children undergo PET insertion each year, making this procedure the most frequently performed pediatric surgery requiring anesthesia. Nevertheless, since conventional PET requir...
متن کاملEarly treatment with everolimus exerts nephroprotective effect in rats with adriamycin-induced nephrotic syndrome.
BACKGROUND Nephrotic syndrome (NS) is a clinical state characterized by massive proteinuria and excessive fluid retention. The effects of early versus late treatment with low or high doses of oral everolimus, a mammalian target of rapamycin inhibitor, on proteinuria in NS have not been previously described. METHODS The effects of early treatment (2 days prior to NS induction) versus late trea...
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ژورنال
عنوان ژورنال: Advances in Clinical and Experimental Medicine
سال: 2016
ISSN: 1899-5276
DOI: 10.17219/acem/22636